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Reduced transforming growth factor β1 (TGF-β1) in the repair of airway epithelial cells of children with asthmaEvidence into the role of TGF-β1 in airway epithelial repair in asthma is still controversial. This study tested the hypothesis that the reduced TGF-β1 levels previously observed in paediatric asthmatic airway epithelial cells directly contribute to the dysregulated repair seen in these cells.
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Immunodominant T-cell epitopes in the VP1 capsid protein of rhinovirus species A and COur results indicate a dissociation between the antibody and T-cell responses to rhinoviruses
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Genome-wide association study of IgG1 responses to the choline-binding protein PspC of Streptococcus pneumoniaeDelayed development of antibodies to S. pneumoniae in infancy is associated with the development of atopy and asthma.
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Infant respiratory infections and later respiratory hospitalisation in childhoodThe aim of this study was to use total-population based data on an otherwise healthy population of children to assess the relationship between early...
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The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma DevelopmentLung inflammation resulting from ARIs during infancy is linked to asthma development.
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Prediction of peri-operative adverse respiratory events in children: The role of exhaled nitric oxide.Increased levels of exhaled nitric oxide (eNO) may be a more objective predictor in identifying children at higher risk of peri-operative adverse respiratory...
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Rationale, design and methods for the 22 year follow-up of the Western Australian Pregnancy Cohort (Raine) StudyYoung adulthood is a critical life period for health and health behaviours.
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The influence of sighing respirations on infant lung function measured using multiple breath washout gas mixing techniquesThere is substantial interest in studying lung function in infants, to better understand the early life origins of chronic lung diseases such as asthma.
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Identification of Der p 23, a peritrophin-like protein, as a new major dermatophagoides pteronyssinus allergenThe house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma.
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Does genetic regulation of IgE begin in utero?Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allerg