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Histone modifications and their role in epigenetics of atopy and allergic diseasesThis review covers basic aspects of histone modification and the role of posttranslational histone modifications in the development of allergic diseases
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Planning ahead: the mental health value of natural environmentsOver the past decade, a growing number of studies have linked urban green space and aspects of biodiversity with emotional wellbeing.
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The effects of maternal smoking on early mucosal immunity and sensitization at 12 months of ageIn this study, we examined the effects of maternal smoking as a major adverse exposure in early life, on mucosal immune function and allergen sensitization...
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A novel role for interleukin-1 receptor signaling in the developmental regulation of immune responses to endotoxinSuggests that IL-1R1 expression provides an additional level of Myd88-dependent signaling during this period of heighted susceptibility to infection.
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Neonatal antigen-presenting cells are functionally more quiescent in children born under traditional compared with modern environmental conditionsOne explanation for the high burden of allergic and autoimmune diseases in industrialized countries is inappropriate immune development under modern...
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T-cell activation genes differentially expressed at birth in CD4+ T-cells from children who develop IgE food allergyTo show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy.
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The relationship between maternal folate status in pregnancy, cord blood folate levels, and allergic outcomes in early childhoodThis study examined whether maternal and/or fetal folate status in pregnancy is associated with infant allergic outcomes.
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Natural environments, nature relatedness and the ecological theater: connecting satellites and sequencing to shinrin-yokuMechanisms-including aerobiological and epigenetic-that might help explain some of the noted positive health outcomes
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World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Vitamin DVitamin D is involved in the regulation of the immune system and it may play a role in the development, severity and course of asthma and other allergic...
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Dysregulation of innate immunity in ulcerative colitis patients who fail anti-tumor necrosis factor therapyStudy the innate immune function in ulcerative colitis patients who fail to respond to anti-tumor necrosis factor therapy