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Research

New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment

We provide evidence that targeting leukemia-induced bone loss is a therapeutic strategy for pre-B ALL

Research

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis

Here we report that CHAF1B is required for normal hematopoiesis while its overexpression promotes leukemia

Research

Measuring the impact of genetic knowledge on intentions and attitudes of the community towards expanded preconception carrier screening

Having good genetic knowledge may not be enough to understand core concepts of preconception carrier screening

Research

Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis

Our data associates IL-1α with early structural lung damage in CF and suggests this pathway as a novel anti-inflammatory target

Research

An economic case for a vaccine to prevent group A streptococcus skin infections

A vaccine that prevents GAS cellulitis and other skin infections, in addition to throat infections, would maximise its value and commercial viability

Research

Use of a primary epithelial cell screening tool to investigate phage therapy in cystic fibrosis

This study demonstrates the feasibility of utilizing pre-clinical in vitro culture models to screen therapeutic candidates

Research

Respiratory Syncytial Virus Hospitalization During Pregnancy in 4 High-income Countries, 2010-2016

This study addressed respiratory syncytial virus (RSV) infection during pregnancy

Research

Global supermarkets' corporate social responsibility commitments to public health: A content analysis

Investigate the world's largest and most powerful supermarkets' publically available CSR commitments to determine their potential impact on public health

Research

Oral health experiences of individuals with Rett syndrome: A retrospective study

Social advantage may provide some protection for dental health in individuals with Rett syndrome