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Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD)The current prophylactic treatment to prevent rheumatic heart disease requires four-weekly intramuscular injection of a suspension of the poorly soluble benzathine salt form of penicillin G (BPG) often for more than 10 years. In seeking to reduce the frequency of administration to improve adherence, biodegradable polymer matrices have been investigated.
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Has the Prevalence of Child and Adolescent Mental Disorders in Australia Changed Between 1998 and 2013 to 2014?This study examined whether the 12-month prevalence of major depressive disorder, attention-deficit/hyperactivity disorder, and conduct disorder among 6- to 17-year-olds in Australia changed between 1998 and 2013 to 2014. It also investigated whether changes in the prevalence of disorders over this time varied for children living in families containing 2 parents versus single parents, and families with high versus low income.
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What is known about consumer nutrition environments in Australia? A scoping review of the literatureThis study aimed to summarize the attributes that have been examined in existing peer-reviewed studies of Australian consumer nutrition environments
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Dysbiotic drift and biopsychosocial medicine: how the microbiome links personal, public and planetary healthHere we focus on the rapidly progressing microbiome science as a way to illustrate the pathways by which exposure to biodiversity supports health
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Histone modifications and their role in epigenetics of atopy and allergic diseasesThis review covers basic aspects of histone modification and the role of posttranslational histone modifications in the development of allergic diseases
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Determining the pneumococcal conjugate vaccine coverage required for indirect protection against vaccine-type pneumococcal carriage in low and middle-income countriesWe will investigate the relationship between PCV coverage and VT carriage among undervaccinated children in Asia and the Pacific
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Lung function trajectories throughout childhood in survivors of very preterm birth: a longitudinal cohort studyLung function trajectories are impaired in survivors of very preterm birth
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Comparable glycemic outcomes for pediatric type 1 diabetes patients in metropolitan and non-metropolitan regions of Western Australia: A population-based studyThis study reports similar glycemic outcomes for patients attending diabetes clinics in metropolitan and non-metropolitan areas of WA
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Defining relevant hypoglycemia measures in children and adolescents with type 1 diabetesAs the choices of therapies in diabetes care multiply, it is essential to standardize the approach to measuring and recording hypoglycemia risk
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Unexpected Management Behaviors in Adolescents With Type 1 Diabetes Using Sensor-Augmented Pump TherapyConstant exposure to real-time data can lead to unsafe management responses in adolescents with the behavior influenced by trust or mistrust in the system