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Research

Mechanisms of IgE sensitization

This project investigates how cells of the immune system respond to substances to cause allergies to help develop new treatments.

News & Events

Can a simple urine test predict asthma? New study aims to find out

The Kids Research Institute Australia researchers are investigating whether a simple urine test could predict whether young children with wheezing symptoms will go on to develop asthma.

News & Events

Annual Community Lecture: You Are What You Breathe

Join us for our Annual Community Lecture entitled "You Are What You Breathe" with Professor Stephen Holgate.

News & Events

Video: The burden of asthma - Michelle's story

Michelle has spent countless nights watching her son struggle to breathe. Our researchers are working to find better treatments for kids living with asthma.

News & Events

Video: The burden of asthma - Karen's story

The Kids Research Institute Australia researchers are at the forefront of asthma research globally. Watch Karen's story to learn why it's so important.

News & Events

Researchers urge caution in how asthma test is used

Researchers are urging caution in the use of a widely accepted test for diagnosing asthma, after their study found it may not be accurate in some settings.

Research

Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics

Our findings provide new insight into the molecular mechanisms operative at baseline in the airway mucosa in atopic asthmatic with natural aeroallergen exposure

Research

Genetic polymorphism of KIR2DL4 (CD158d), a putative NK cell receptor for HLA-G, does not influence susceptibility to asthma

No reproducible associations with KIR2DL4 genotype were identified, leading us to conclude that the KIR2DL4 9A/10A polymorphism has no influence...

Research

Immune modulation by UV: Role of vitamin D

In this chapter, evidence for and evidence against the involvement of vitamin D in the immunoregulatory properties of UV radiation is presented.

Research

Relationship between cytokine expression patterns and clinical outcomes: two population-based birth cohorts

Our findings suggest that positive HDM 'allergy tests' and asthma are associated with a broad range of immunophenotypes, which may have important...