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Research

Developing national guidelines for intervention with children on the autism spectrum in Australia

Investigators: Prof Andrew Whitehouse, Prof David Trembath Project description This project involves developing a national practice guideline for

Research

Editorial: Insights Into Biomarkers, Cytokines, and Chemokines in Skin Cancer

Our current Research Topic highlights the complexity of the relationship between the skin, immune system and skin cancer

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Dendritic cells and cancer: From biology to therapeutic intervention

In this review, we discuss the different subsets of tumor-infiltrating dendritic cells and their role in anti-tumor immunity

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CD8+XCR1neg Dendritic Cells Express High Levels of Toll-Like Receptor 5 and a Unique Complement of Endocytic Receptors

Our data demonstrate that CD8+XCR1neg DCs possess a unique pattern of endocytic receptors and a restricted TLR profile that is particularly enriched for TLR5

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Changes in cell morphology guide identification of tubulin as the off-target for protein kinase inhibitors

Early changes in cell morphology upon treatments are a strong indication that the inhibitor is directly targeting tubulin

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Cross-presentation of cutaneous melanoma antigen by migratory XCR1+CD103− and XCR1+CD103+ dendritic cells

This report provides new insight into the functional specialization within the broad network of dendritic cells that are responsible for skin immunosurveillance

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A randomised-controlled trial of a behavioural intervention for optimising social and communication development in newborns at increased likelihood of autism spectrum disorders

Andrew Kandice Matt Melissa Videos Whitehouse Watch and listen to Andrew Varcin Cooper Licari PhD M.Psych (Clinical), PhD BCA Marketing, BSc

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T cells recognizing a 11mer influenza peptide complexed to H-2D b show promiscuity for peptide length

T-cell repertoire is selected according to self peptide-MHC (major histocompatibility complex) complexes in the thymus.

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The CliniBank Study: A research project to improve future clinical supports for children experiencing developmental difficulties

Andrew Gemma Gail Videos Whitehouse Watch and listen to Andrew Upson Alvares PhD BSc MClinAud MBA PhD Deputy Director (Research); Angela Wright

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Renal Masses in Childhood: An Australian Perspective

Childhood renal masses comprise a heterogeneous group of conditions that have a wide range of presentations. This review outlines an approach to the diagnostic work-up of childhood renal masses and discusses the most common presentations and treatments. Renal tumours make up 5% of childhood cancer in Australia, with Wilms tumour being the most common under age 10 years.

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Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrow

Injection of BM-differentiated DCs from nonchimeric mice restored the reduced immune responses of PGE2-chimeric mice.

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A randomised-controlled trial of a parent-mediated intervention for managing uncertainty in young children diagnosed on the autism spectrum

Gail Andrew Videos Alvares Whitehouse Watch and listen to Andrew PhD PhD Principal Research Fellow Deputy Director (Research); Angela Wright Bennett

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Assistance and Companion Dogs for children diagnosed with Autism Spectrum Disorder and Fragile X

Andrew Gail Videos Whitehouse Watch and listen to Andrew Alvares PhD PhD Deputy Director (Research); Angela Wright Bennett Professor of Autism

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Effect of an exercise intervention (Move2Engage: Youth) on activity levels, quality of sleep and mental health outcomes in children and youth with movement difficulties

Melissa Andrew Gail Jenny Videos Licari Whitehouse Watch and listen to Andrew Alvares Downs PhD PhD PhD BApplSci (physio) MSc PhD Senior Research