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Cross-protective efficacy of HPV-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types

We evaluated the efficacy of the human papillomavirus HPV-16/18 AS04-adjuvanted vaccine against non-vaccine oncogenic HPV types.

Initial assessment of the StepWatch Activity Monitor™ to measure walking activity in Rett syndrome

In girls and women with Rett syndrome, we assessed the accuracy of the StepWatch Activity Monitor™ and investigated relationships between daily step counts,...

Symptomatic viral infection is associated with impaired response to treatment in children with acute asthma

The objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children.

Parental prenatal smoking and risk of childhood acute lymphoblastic leukemia

The association between parental smoking and risk of childhood acute lymphoblastic leukemia (ALL) was investigated

Pre-natal, clonal origin of t(1;11)(p32;q23) acute lymphoblastic leukemia in monozygotic twins

Investigation of this rare mixed lineage leukemia cytogenetic abnormality aims to provide further evidence of the genetic changes that underpin this leukemia.

Peptides targeting the mitogen-activated protein kinase pathway (JNK/JUN) fail to reduce infarct volume after permanent MCAO in sprague dawley rats

In this study we have assessed the ability of two TAT-fused peptides to reduce infarct volume and improve functional outcome following permanent ischaemia.

Histiologic chorioamnionitis is associated with reduced incidence of late-onset sepsis in very preterm infants

Histologic chorioamnionitis (HCA) is implicated in the onset of preterm labor and delivery. Chorioamnionitis is a known risk factor for early-onset sepsis...

Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivo

The objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo.

Sterile abscess formation associated with depot leuprorelin acetate therapy for central precocious puberty

We describe a case of an 8 year old girl with central precocious puberty. She was commenced on 3 monthly intramuscular depot Leuprorelin acetate therapy, as...

Interferon regulatory factor 7 is a major hub connecting interferon-mediated responses in virus-induced asthma exacerbations in vivo

The objective of this study was to elucidate the molecular networks that underpin virus-induced exacerbations in asthmatic children in vivo.